Message from CEO, William Shell M.D

Physician Therapeutics is a specialty pharmaceutical company that provides a range of prescription Medical Food products and a line of traditional generic drugs. The goal of the Company is to provide safe and effective therapeutic products for patients with certain disease states, who are under the ongoing care of a physician. The Company has spent many years developing novel Medical Food products that address the nutrient requirements of diseases such as fibromyalgia, pain syndromes, sleep disorders, metabolic syndromes, hypertension, and asthma.

All Medical Food products use Targeted Cellular Technology™ a patented process that allows very small quantities of neurotransmitter precursors to enter the cells and produce specific neurotransmitters*. (see patent information below)

This five component system includes:

1. A neurotransmitter precursor supplied as an amino acid
2. A neuronal uptake stimulator
3. A neuron activator
4. An adenosine antagonist, such to dis-inhibit the neuron
5. An attenuation inhibitor of the precursor response a well known precursor phenomena

This proprietary application of neurotransmitter science is designed to promote the production and release of the neurotransmitters norepinephrine, epinephrine, dopamine, serotonin, acetylcholine, histamine, glutamine and nitric oxide.

The use of a specific Medical Food product prescribed with a specific drug has been shown in clinical trials to allow a pharmaceutical agent to be used effectively at very low dose.

The Company’s Medical Food products include Theramine, Sentra PM, GABAdone, Sentra AM, Hypertensa, AppTrim, Pulmona, Lister V and Trepadone.

Theramine stimulates the nitric oxide/serotonin neurotransmitters that address the increased nutrient requirements in acute and chronic pain.

Sentra PM stimulates the choline/serotonin neurotransmitters to nutritionally modulate sleep cycles and addresses the nutritional requirements in sleep disorders associated with depression.

GABAdone stimulates the choline/GABA neurotransmitters to nutritionally modulate sleep cycles and addresses the nutritional requirements in sleep disorders associated with anxiety.

Sentra AM stimulates the acetylcholine neurotransmitters to nutritionally modulate cognition and fatigue and addresses the nutritional requirements of autonomic nervous system disorders including fibromyalgia.

Hypertensa stimulates the nitric oxide/choline neurotransmitters that nutritionally modulate arterial flexibility and addresses the nutritional requirements of hypertension and metabolic syndrome.

AppTrim stimulates the serotonin/norepinephrine neurotransmitters to nutritionally modulate insulin resistance and addresses the nutritional requirements of metabolic syndrome associated with obesity.

Pulmona stimulates the nitric oxide neurotransmitters to nutritionally modulate pulmonary artery flexibility and bronchial resistance and addresses the nutritional requirements of pulmonary hypertension and asthma.

Lister V stimulates nitric oxide to nutritionally modulate white blood cell production and
addresses the nutritional requirements of immune function as it pertains to infection control.

Trepadone stimulates nitric oxide neurotransmitters and supplies chondroitin, glucosamine and
omega 3 fatty acids and addresses pain and inflammation of the joints.

These disease states have distinct nutritional requirements as outlined in the product
monographs.

Physician Therapeutics validates its products using the Evidence Based Medicine guidance
recommended by the FDA. The FDA has developed criteria for evaluating the large body of
information that is required to assess the value of therapeutic interventions. In the FDA guidance
program, the type, quantity, and consistency of evidence is evaluated and graded.

Company products are distributed through physicians with prescription only requirements. Clinical
experience has shown that Medical Foods used alone or with traditional drugs have a low side
effect profile, while maintaining the desired therapeutic effect.

Physician Therapeutics’ proprietary products provide a novel approach to the management of
disease states for which past therapies have often resulted in unacceptable side effects.

Thank you for taking the time to visit our website. We are committed to providing you with the
help you need to understand our products.

Sincerely,

William Shell M.D.
CEO and Chief Scientific Officer
Physician Therapeutics

 

*Patent information:

1. 7,674,482 Method and compositions for potentiating pharmaceuticals with amino acid based medical foods
2. 7,601,369 Composition and method to augment and sustain neurotransmitter production
3. 7,595,067 Composition and method to augment and sustain neurotransmitter production
4. 7,585,523 Composition and method to augment and sustain neurotransmitter production
5. 7,582,315 Composition and method to augment and sustain neurotransmitter production